Highlights of the Mouse Brain Architecture Project

Myelin stained Sagittal Section of Mouse Brain.

Series: Myelin stained sagittal series (Mouse Brain 0001) Approximate Section Location: Bregma 0.0mm Imaging Method: Brightfield Label Method: IHC Color Range (RGB): 0-255,0-255,0-255, Gamma: 1

Ascending Secondary Visual Pathway: Tectum to Thalamus projection (BDA).

Series: MouseBrain_0413 IHC Approximate Section Location: Bregma -2.64mm Imaging Method: Brightfield Label Method: IHC Injection: BDA10k (0.30 mm, -3.78 mm, 0.95 mm) Color Range (RGB): 0-255,0-255,0-255, Gamma: 1

Projections to Mamillary Nucleus (via Fornix) from Subiculum (BDA).

Series: MouseBrain_0498 IHC Approximate Section Location: Bregma -2.36mm Imaging Method: Brightfield Label Method: IHC Injection: BDA10k (2.18 mm, -3.63 mm, 1.90 mm) Color Range (RGB): 0-255,0-255,0-255, Gamma: 1.2

Projections from a Motor Cortex AAV injection

Series: MouseBrain_0841 F Approximate Section Location: Bregma -0.6mm Imaging Method: Fluorescent Label Method: Fluorescent Injection: AAV2/1 CAG (1.10 mm, -0.50 mm, 0.75 mm) Color Range (RGB): 0-2703,0-1392,0-1269, Gamma: 0.8

Projections from Motor Cortex traced with BDA

Series: MouseBrain_0887 IHC Approximate Section Location: Bregma +0.2mm Imaging Method: Brightfield Label Method: IHC Injection: BDA10k (1.10 mm, 0.60 mm, 0.95 mm) Color Range (RGB): 0-255,0-255,0-255, Gamma: 1

Retrogradely labelled cells Contralateral to the Injection in Parietal Cortex (RV).

Series: MouseBrain_0967 F Approximate Section Location: Bregma -2.08mm Imaging Method: Fluorescent Label Method: Fluorescent Injection: RV-4GFP(B19G) ("Retrograde") (2.00 mm, -2.48 mm, 0.50 mm) Color Range (RGB): 0-255,0-255,0-255, Gamma: 1

Parvalbumin Positive GABAergic cells (Nuclear GFP label)

Series: Cre-dependent nuclear GFP (H2B-GFP) in Parvalbumin (PV)+ soma-targeting class of GABAergic cells (collaboration wit Approximate Section http://mouse.brainarchitecture.org/seriesbrowser/viewer/1642/280943 Location: Bregma -1.0mm Imaging Method: Fluorescent Label Method: Fluorescent Color Range (RGB): 0-255,0-255,0-255, Gamma: 1

The Mouse Brain Architecture Project produces many striking neuroanatomical images. Here are a few examples to provide a convenient entry point to some of the material.

Click on any image to browse the corresponding whole brain.